Prepolarized MRI at Earth Field to seek new contrasts linked to molecular events for very early detection of pathologies

Discover the project


PrimoGaia opens up a new pathway in Magnetic Resonance Imaging (MRI) by initiating the concept of in vivo “enzymatic imaging” for a better understanding of human physiology, early detection and prognosis of diseases, monitoring of therapeutic treatment.

The project

7 partners
4 countries
H2020 FET Open
Start: 01-12-2019
end: 31-05-2023

#magnetic resonance imaging (MRI), #dynamic nuclear polarization (DNP), #overhauser MRI (OMRI), #enzyme activity, #ultra-low field, #contrast agents, #inflammatory diseases, #enzymatic mapping, #cost efficient sytems, #medical engineering
Final public conference
Final Conference
PrimoGAIA Final Steering Committee meeting
The PrimoGAIA Final Steering Committee was held in Bordeaux, France, on the 16th of October 2023
4-Amino-TEMPO loaded liposomes as EPR probes for detection of phospholipase A2 activity
Published in Chemistry Europe
Philippe Massot presented the Overhauser enhanced MRI imaging techniques at Euro-BioImaging
1st Workshop on Emerging Trends in Molecular Imaging 2023
We are pleased to announce the first workshop on Emerging Trends in Molecular Imaging, jointly organised by the Molecular Imaging Center (CIM) – Uni...
A system for in vivo on-demand ultra-low field Overhauser-enhanced 3D-Magnetic resonance imaging
Pubished in the Journal of Magnetic Resonance
PrimoGAIA 3rd Steering Committee meeting
The PrimoGAIA 2nd Steering Committee was held in Turin, Italy, on the 13th of September 2022
Neutrophil Elastase-Activatable Prodrugs Based on an Alkoxyamine Platform to Deliver Alkyl Radicals Cytotoxic to Tumor Cells
Published in Chemistry Europe
2nd Periodic report
Periodic Reporting for period 2 - PRIMOGAIA