The University of Turin (UT) is one of the most ancient and prestigious Italian Universities. Hosting over 74.000 students and with 120 buildings in different areas in Turin and in key places in Piedmont, the University of Turin can be considered as “city-within-a-city”, promoting culture and producing research, innovation, training and employment. UT is today one of the largest Italian Universities, open to international research and training. The Center for Molecular Imaging (CIM) of UT, which will be directly involved in this project, is coordinated by prof, S. Aime. CIM was founded by chemists, biologists physicians in 2001 with the aim of developing new diagnostic procedures based on the visualization of molecules or molecular events biomarkers for an earlier detection of the disease.

Simonetta Geninatti Crich

She is the person in charge of the proposal for UNITO. She is responsible of the development of activable prodrugs (proradicals) loaded into Liposomes and other nanoparticles (i.e. polylactic and glycolic acid-based NP, hydrogels) responsive to specific enzymatic activity. She is WP5 leader.

Graduated in Chemistry in 1993 and she got her Ph.D. in Biochemical Sciences at the University of Torino (Italy) in 1997. She is Associate Professor of General and Inorganic Chemistry at the Molecular Biotechnology and Health Sciences department. She is co-author of 97 original scientific papers in peer reviewed journals (H-index 36), 5 patents and 2 book chapters. She has given about 45 oral presentations nationally and internationally. She is member of ISNCT (International Congress on Neutron Capture Therapy) Executive Board (2016-2020) and of the GIDRM (Gruppo italiano risonanze magnetiche) Executive Board (2019-2023). Her current research is focused on the development and preparation of nanosized agents for the delivery of both therapeutic and MRI agents, on the setup of efficient cellular labeling procedures for both “in vitro” and “in vivo” pre-clinical models and on the development of innovative contrast agents for low field FFC-MRI applications.

Prof. Silvio Aime

As leader of the Molecular Imaging Center of UNITO he will coordinate the activity that will be perfomed in the center.

Is Professor of General and Inorganic Chemistry at the Department of Molecular Biotechnologies and Health Sciences and Head of the Center of Excellence on Molecular Imaging of the University of Torino.
His main research activities deal with the development of Imaging Probes for MR-Molecular Imaging applications (paramagnetic complexes, nanoparticles, CEST agents, targeting and responsive probes, hyperpolarized Para-Hydrogen containing molecules). In the last decade his research interests have included the design and testing of imaging probes for other imaging modalities (nuclear, optical and photoacoustic imaging). Recent awards: 2013: World Molecular Imaging Society Gold Medal Award; 2013: Fischer Award for Contrast Media Research; 2014: Gold Medal “Amedeo Avogadro” from the Italian Chemical Society; 2016: Member of the Accademia dei Lincei..

Diego Alberti PhD

He is working on EPR silent liposomes responsive to specific enzymatic activity for the project.

Graduated in Molecular Biotechnology in 2008, he got his PhD in 2012 in Bio-Chemical Sciences of the School of Science and High Technology at the University of Torino. He is a research technician working on PrimoGaia european project. His experience concerns the development and characterization of innovative nano-systems for molecular imaging and theranostic applications.

Dr. Sabrina Elkhanoufi

PhD student working for the project

Sabrina Elkhanoufi has a Master’s degree in Chemistry from University of Torino (Italy).